Since the early 2000s, a substantial body of peer-reviewed research has investigated the utility of nicotine vaping products (tNVPs) as quit smoking aids. This evidence base continues to develop, with studies considering product characteristics, patterns of use, and potential public health implications.

Earlier research often focused on comparisons with combustible tobacco products. More recent work has explored the role of therapeutic nicotine vaping products within smoking cessation and nicotine dependence management in clinical and population settings.

Product design and formulations continue to evolve, with ongoing research assessing their safety, quality, and use within appropriate regulatory frameworks.